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C2orf40 Blocking Peptide(N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H1Z8 |
|---|---|
| Other Accession | NP_115787.1 |
| Gene ID | 84417 |
|---|---|
| Other Names | Augurin, Esophageal cancer-related gene 4 protein, C2orf40, ECRG4 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 66-79 of HUMAN C2orf40 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ECRG4 (HGNC:24642) |
|---|---|
| Synonyms | C2orf40 |
| Function | Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity). |
| Cellular Location | Secreted. Cytoplasm. Apical cell membrane |
| Tissue Location | Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
C2orf40 is probable hormone.
References
Li, W., et al. J. Exp. Clin. Cancer Res. 29, 89 (2010) :
Li, L.W., et al. Int. J. Cancer 125(7):1505-1513(2009)
Gotze, S., et al. BMC Cancer 9, 447 (2009) :
Mori, Y., et al. Oncol. Rep. 18(4):981-985(2007)
Mirabeau, O., et al. Genome Res. 17(3):320-327(2007)
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