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RXFP1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q9HBX9
Other Accession NP_067647.2
Additional Information
Gene ID 59350
Other Names Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1, RXFP1, LGR7
Target/Specificity The synthetic peptide sequence is selected from aa 700-713 of HUMAN RXFP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RXFP1
Synonyms LGR7
Function Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
Research Areas
Citations (0)

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Background

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

References

Halls, M.L., et al. EMBO J. 29(16):2772-2787(2010)
Singh, S., et al. Mol. Cell. Endocrinol. 315 (1-2), 239-245 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Feng, S., et al. Ann. N. Y. Acad. Sci. 1160, 379-380 (2009) :
Li, Z., et al. Ann. N. Y. Acad. Sci. 1160, 374-378 (2009) :

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$ 80.00
Cat# BP19927B
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