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HOXC10 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NYD6 |
|---|---|
| Other Accession | P31257, NP_059105.2 |
| Gene ID | 3226 |
|---|---|
| Other Names | Homeobox protein Hox-C10, Homeobox protein Hox-3I, HOXC10, HOX3I |
| Target/Specificity | The synthetic peptide sequence is selected from aa 239-250 of HUMAN HOXC10 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HOXC10 |
|---|---|
| Synonyms | HOX3I |
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.
References
Hwang, J.H., et al. Cloning Stem Cells 11(2):269-279(2009)
Zhai, Y., et al. Cancer Res. 67(21):10163-10172(2007)
Gabellini, D., et al. EMBO J. 22(14):3715-3724(2003)
Kosaki, K., et al. Teratology 65(2):50-62(2002)
Sandrock, B., et al. J. Biol. Chem. 276(38):35328-35333(2001)
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