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POPD3 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9HBV1 |
|---|---|
| Other Accession | NP_071756.2 |
| Gene ID | 64208 |
|---|---|
| Other Names | Popeye domain-containing protein 3, Popeye protein 3, POPDC3, POP3 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 246-259 of HUMAN POPDC3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | POPDC3 |
|---|---|
| Synonyms | POP3 |
| Function | May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding. May play a role in the regulation of KCNK2/TREK-1-mediated current amplitude (PubMed:31610034). |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Expressed predominantly in skeletal muscle (at protein level) (PubMed:10882522, PubMed:31610034). Also detected in heart (PubMed:10882522). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development. Alternatively spliced transcript variants have been found.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kim, M., et al. Carcinogenesis 31(9):1685-1693(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Sulem, P., et al. Nat. Genet. 41(6):734-738(2009)
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