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SEC31A Blocking Peptide (Center)

Synthetic peptide

Product Information
Primary Accession O94979
Other Accession NP_055748.2
Additional Information
Gene ID 22872
Other Names Protein transport protein Sec31A, ABP125, ABP130, SEC31-like protein 1, SEC31-related protein A, Web1-like protein, SEC31A, KIAA0905, SEC31L1
Target/Specificity The synthetic peptide sequence is selected from aa 488-502 of HUMAN SEC31A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC31A
Synonyms KIAA0905, SEC31L1
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Cellular Location Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein Note=Associates with membranes in a GTP-dependent manner
Tissue Location Abundantly and ubiquitously expressed.
Research Areas
Citations (0)

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The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Townley, A.K., et al. J. Cell. Sci. 121 (PT 18), 3025-3034 (2008) :
Stagg, S.M., et al. Cell 134(3):474-484(2008)
Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)
Bi, X., et al. Dev. Cell 13(5):635-645(2007)

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$ 80.00
$ 99.00
Cat# BP20163C
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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