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GTF2F2 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P13984 |
|---|---|
| Other Accession | Q01750, Q8R0A0, Q2T9L9, NP_004119.1 |
| Gene ID | 2963 |
|---|---|
| Other Names | General transcription factor IIF subunit 2, ATP-dependent helicase GTF2F2, General transcription factor IIF 30 kDa subunit, Transcription initiation factor IIF subunit beta, TFIIF-beta, Transcription initiation factor RAP30, GTF2F2, RAP30 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 159-172 of HUMAN GTF2F2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GTF2F2 |
|---|---|
| Synonyms | RAP30 |
| Function | TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
References
Yang, A., et al. Biochemistry 48(9):1964-1974(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Le, T.T., et al. J. Biochem. 138(3):215-224(2005)
Kim, J.E., et al. J. Proteome Res. 4(4):1339-1346(2005)
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