MEG11 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | A6BM72 |
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Other Accession | Q80T91, NP_115821.2 |
Gene ID | 84465 |
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Other Names | Multiple epidermal growth factor-like domains protein 11, Multiple EGF-like domains protein 11, MEGF11, KIAA1781 |
Target/Specificity | The synthetic peptide sequence is selected from aa 65-79 of HUMAN MEGF11 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MEGF11 |
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Synonyms | KIAA1781 |
Function | May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein Basolateral cell membrane; Single-pass type I membrane protein. Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10 |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Suzuki, E., et al. Exp. Cell Res. 313(11):2451-2464(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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