|Other Accession||Q80T91, NP_115821.2|
|Other Names||Multiple epidermal growth factor-like domains protein 11, Multiple EGF-like domains protein 11, MEGF11, KIAA1781|
|Target/Specificity||The synthetic peptide sequence is selected from aa 65-79 of HUMAN MEGF11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Basolateral cell membrane; Single- pass type I membrane protein Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein is unknown.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Suzuki, E., et al. Exp. Cell Res. 313(11):2451-2464(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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