|Other Accession||P62634, P53996, O42395, Q3T0Q6, NP_001120665.1|
|Other Names||Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9|
|Target/Specificity||The synthetic peptide sequence is selected from aa 106-118 of HUMAN CNBP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.|
|Cellular Location||Cytoplasm. Endoplasmic reticulum|
|Tissue Location||Present in all tissues examined.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalli, C., et al. J Mol Diagn 12(5):601-606(2010)
Massa, R., et al. Neuropathol. Appl. Neurobiol. 36(4):275-284(2010)
Sammons, M.A., et al. PLoS ONE 5 (2), E9301 (2010) :
Lucchiari, S., et al. J. Neurol. Sci. 275 (1-2), 159-163 (2008) :
Auvinen, S., et al. Arthritis Rheum. 58(11):3627-3631(2008)
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