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MOUSE Bcar1 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q61140 |
|---|---|
| Other Accession | Q63767 |
| Gene ID | 12927 |
|---|---|
| Other Names | Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, p130cas, Bcar1, Cas, Crkas |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Bcar1 |
|---|---|
| Synonyms | Cas, Crkas |
| Function | Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (By similarity). Implicated in induction of cell migration and cell branching (PubMed:25499443). Involved in the BCAR3-mediated inhibition of TGFB signaling (PubMed:25499443). |
| Cellular Location | Cell junction, focal adhesion. Cytoplasm Cell projection, axon Note=Unphosphorylated form localizes in the cytoplasm (PubMed:22801373). Localizes to focal adhesion sites following integrin engagement (PubMed:22801373). |
| Tissue Location | Expressed in olfactory sensory neurons (at protein level) (PubMed:20881139). Expressed abundantly in the liver, lung, brain, and at lower levels in the heart (at protein level) (PubMed:19365570). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration (By similarity). Has been shown to be essential in cardiovascular development during embryogenesis.
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