|Other Names||Granulins, Proepithelin, PEPI, Acrogranin, Glycoprotein of 88 Kda, Progranulin, Paragranulin, Granulin-1, Granulin G, Granulin-2, Granulin F, Granulin-3, Granulin B, Granulin-4, Granulin A, Granulin-5, Granulin C, Granulin-6, Granulin D, Granulin-7, Granulin E, GRN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.|
|Tissue Location||In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
Bhandari V., et al. Biochem. Biophys. Res. Commun. 188:57-63(1992).
Plowman G.D., et al. J. Biol. Chem. 267:13073-13078(1992).
Bhandari V., et al. Proc. Natl. Acad. Sci. U.S.A. 89:1715-1719(1992).
Lu R., et al. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Yu W., et al. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
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