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TSPYL2 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H2G4 |
|---|---|
| Other Accession | Q9BE64 |
| Gene ID | 64061 |
|---|---|
| Other Names | Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TSPYL2 |
|---|---|
| Synonyms | CDA1, DENTT, TSPX |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Cellular Location | Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons |
| Tissue Location | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
References
Dephoure N., et al. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Chai Z., et al. J. Biol. Chem. 276:33665-33674(2001).
Eichmueller S., et al. Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001).
Bechtel S., et al. BMC Genomics 8:399-399(2007).
Ross M.T., et al. Nature 434:325-337(2005).
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