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TSPYL2 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9H2G4
Other Accession Q9BE64
Additional Information
Gene ID 64061
Other Names Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSPYL2
Synonyms CDA1, DENTT, TSPX
Function Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Cellular Location Nucleus. Cytoplasm Note=Enriched in transcriptionally active regions of chromatin in neurons.
Tissue Location Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas
Research Areas
Citations (0)

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Background

Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.

References

Dephoure N., et al. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Chai Z., et al. J. Biol. Chem. 276:33665-33674(2001).
Eichmueller S., et al. Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001).
Bechtel S., et al. BMC Genomics 8:399-399(2007).
Ross M.T., et al. Nature 434:325-337(2005).

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$ 80.00
$ 99.00
Cat# BP20456c
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