SAP30BP Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UHR5 |
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Other Accession | Q02614 |
Gene ID | 29115 |
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Other Names | SAP30-binding protein, Transcriptional regulator protein HCNGP, SAP30BP {ECO:0000312|EMBL:AAH075921} |
Target/Specificity | The synthetic peptide sequence is selected from aa 175-188 of Human SAP30BP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SAP30BP {ECO:0000312|EMBL:AAH07592.1} |
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Function | Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3 (PubMed:21221920). May be involved in the regulation of beta-2- microglobulin genes (By similarity). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes.
References
Li J.-F., et al. J. Biochem. 136:169-176(2004).
Gou D., et al. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ding J.B., et al. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Hu R.-M., et al. Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Ota T., et al. Nat. Genet. 36:40-45(2004).
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