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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P49721 |
|---|---|
| Other Accession | P40307, Q9R1P3 |
| Gene ID | 5690 |
|---|---|
| Other Names | Proteasome subunit beta type-2, Macropain subunit C7-I, Multicatalytic endopeptidase complex subunit C7-I, Proteasome component C7-I, PSMB2 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 149-163 of Human PSMB2 |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PSMB2 |
|---|---|
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity. |
| Cellular Location | Cytoplasm. Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity.
References
Lubec G., et al. Submitted (MAR-2007) to UniProtKB.
Rasmussen H.H., et al. Electrophoresis 13:960-969(1992).
Kristensen P., et al. Biochem. Biophys. Res. Commun. 205:1785-1789(1994).
Apcher G.S., et al. FEBS Lett. 553:200-204(2003).
Nothwang H.G., et al. Biochim. Biophys. Acta 1219:361-368(1994).
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