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GDF11 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95390
Clone Names 2081005
Peptide ID 2081005
Additional Information
Gene ID 10220
Other Names Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2061a was selected from the N-term region of human GDF11 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDF11
Synonyms BMP11
Function Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Cellular Location Secreted.
Research Areas
Citations (0)

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GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.


Lee, S.J., et al., Curr. Opin. Genet. Dev. 9(5):604-607 (1999).McPherron, A.C., et al., Nat. Genet. 22(3):260-264 (1999).Gamer, L.W., et al., Dev. Biol. 208(1):222-232 (1999).Hillier, L.D., et al., Genome Res. 6(9):807-828 (1996).

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$ 80.00
Cat# BP2061a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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