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STOM Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P27105 |
|---|
| Gene ID | 2040 |
|---|---|
| Other Names | Erythrocyte band 7 integral membrane protein, Protein 72b, Stomatin, STOM, BND7, EPB72 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 2-16 of HUMAN STOM |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | STOM (HGNC:3383) |
|---|---|
| Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
| Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190) Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). |
| Tissue Location | Detected in erythrocytes (at protein level). Widely expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating (By similarity).
References
Hiebl-Dirschmied C.M.,et al.Biochim. Biophys. Acta 1090:123-124(1991).
Stewart G.W.,et al.Blood 79:1593-1601(1992).
Unfried I.,et al.Genomics 30:521-528(1995).
Gallagher P.G.,et al.J. Biol. Chem. 270:26358-26363(1995).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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