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RSF1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q96T23
Additional Information
Gene ID 51773
Other Names Remodeling and spacing factor 1, Rsf-1, HBV pX-associated protein 8, Hepatitis B virus X-associated protein, p325 subunit of RSF chromatin-remodeling complex, RSF1, HBXAP, XAP8
Target/Specificity The synthetic peptide sequence is selected from aa 1355-1369 of HUMAN RSF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RSF1
Synonyms HBXAP, XAP8
Function Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex (PubMed:12972596). Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain (PubMed:11944984, PubMed:11788598).
Cellular Location Nucleus
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.

References

Shamay M.,et al.Genomics 79:523-529(2002).
Shamay M.,et al.J. Biol. Chem. 277:9982-9988(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mao Y.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 80.00
Cat# BP20734c
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