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Human-AHCTF1 (S1232) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8WYP5
Additional Information
Gene ID 25909
Other Names Protein ELYS, Embryonic large molecule derived from yolk sac, Protein MEL-28, Putative AT-hook-containing transcription factor 1, AHCTF1, ELYS, TMBS62
Target/Specificity The synthetic peptide sequence is selected from aa 1210-1240 of HUMAN AHCTF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AHCTF1
Synonyms ELYS, TMBS62
Function Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
Cellular Location Cytoplasm. Nucleus matrix. Chromosome, centromere, kinetochore. Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107- 160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase
Research Areas
Citations (0)

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Background

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

References

Kimura N.,et al.Genes Cells 7:435-446(2002).
Lightfoot J.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Liu B.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
Cat# BP20765b
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