|Other Accession||O08589, Q9Z239, Q3SZX0|
|Other Names||Phospholemman, FXYD domain-containing ion transport regulator 1, FXYD1, PLM|
|Target/Specificity||The synthetic peptide sequence is selected from aa 69-81 of HUMAN FXYD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis|
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May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Chen L.-S.K.,et al.Genomics 41:435-443(1997).
Sweadner K.J.,et al.Genomics 68:41-56(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mounsey J.P.,et al.J. Biol. Chem. 275:23362-23367(2000).
Tulloch L.B.,et al.J. Biol. Chem. 286:36020-36031(2011).
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