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Mouse Ror2 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q9Z138
Other Accession Q01974
Additional Information
Other Names Tyrosine-protein kinase transmembrane receptor ROR2, mROR2, Neurotrophic tyrosine kinase, receptor-related 2, Ror2
Target/Specificity The synthetic peptide sequence is selected from aa 756-770 of HUMAN Ror2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ror2
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (PubMed:10700181). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (By similarity).

References

Oishi I.,et al.Genes Cells 4:41-56(1999).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
DeChiara T.M.,et al.Nat. Genet. 24:271-274(2000).
van Wijk N.V.,et al.Biochem. Biophys. Res. Commun. 390:211-216(2009).

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$ 80.00
Cat# BP20846c
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