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RBBP5 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q15291
Other Accession Q8BX09
Additional Information
Gene ID 5929
Other Names Retinoblastoma-binding protein 5, RBBP-5, Retinoblastoma-binding protein RBQ-3, RBBP5, RBQ3
Target/Specificity The synthetic peptide sequence is selected from aa 451-465 of HUMAN RBBP5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBBP5
Synonyms RBQ3
Function In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

References

Saijo M.,et al.Genomics 27:511-519(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hughes C.M.,et al.Mol. Cell 13:587-597(2004).

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$ 80.00
$ 99.00
Cat# BP20943c
Size:
Quantity:
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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