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GNL3 Blocking Peptide (N-term)

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession Q9BVP2
Other Accession Q8CI11
Additional Information
Gene ID 26354
Other Names Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, Nucleolar GTP-binding protein 3, Nucleostemin, GNL3, E2IG3, NS
Target/Specificity The synthetic peptide sequence is selected from aa 38-52 of HUMAN GNL3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNL3
Synonyms E2IG3, NS
Function May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus Note=Shuttles between the nucleus and nucleolus {ECO:0000250|UniProtKB:Q811S9}
Tissue Location Increased levels in lung tissue in cancer patients.
Research Areas
Citations (0)

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Background

May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity).

References

Charpentier A.H.,et al.Cancer Res. 60:5977-5983(2000).
Han C.,et al.Int. J. Mol. Med. 16:205-213(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Andersen J.S.,et al.Curr. Biol. 12:1-11(2002).

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$ 80.00
Cat# BP20949b
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