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(Mouse) Msi1 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q61474
Other Accession Q8K3P4, O43347
Additional Information
Gene ID 17690
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, Msi1, Msi1h
Target/Specificity The synthetic peptide sequence is selected from aa 81-93 of HUMAN Msi1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Msi1
Synonyms Msi1h
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in olfactory bulb, brain stem, small intestine, and at low levels in brain cortex, hippocampus and ovary. Detected in neural progenitor cells, including neural stem cells.
Research Areas
Citations (0)

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Background

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

References

Sakakibara S.,et al.Dev. Biol. 176:230-242(1996).
Carninci P.,et al.Science 309:1559-1563(2005).
Imai T.,et al.Mol. Cell. Biol. 21:3888-3900(2001).
Sakakibara S.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:15194-15199(2002).
Nagata T.,et al.J. Mol. Biol. 287:315-330(1999).

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$ 80.00
Cat# BP20967a
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Availability: 2 weeks
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