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Mouse Pax6 Blocking Peptide (C-term)

Synthetic peptide

     
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  • CITATIONS
  • PROTOCOLS
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Product Information
Primary Accession P63015
Other Accession P55864, P63016, P26367, P26630, P47237, Q1LZF1
Additional Information
Gene ID 18508
Other Names Paired box protein Pax-6, Oculorhombin, Pax6, Pax-6, Sey
Target/Specificity The synthetic peptide sequence is selected from aa 404-416 of HUMAN Pax6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pax6
Synonyms Pax-6, Sey
Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 3 are the major isoforms among different eye tissues. Isoform 1 and isoform 3 are expressed in the retina and cornea. In the lens epithelium, isoform 1 is relatively abundant, but isoform 3 is barely detectable
Research Areas
Citations (0)

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Background

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).

References

Walther C.,et al.Development 113:1435-1449(1991).
Favor J.,et al.Genetics 159:1689-1700(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
Walther C.,et al.Genomics 11:424-434(1991).
Ton C.C.T.,et al.Genomics 13:251-256(1992).

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$ 80.00
$ 99.00
Cat# BP21096a
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