|Other Names||POC1 centriolar protein homolog A, Pix2, Proteome of centriole protein 1A, WD repeat-containing protein 51A, POC1A, WDR51A|
|Target/Specificity||The synthetic peptide sequence is selected from aa 326-340 of HUMAN POC1A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole Note=Component of both mother and daughter centrioles|
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Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.
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Hames R.S.,et al.Exp. Cell Res. 314:574-589(2008).
Pearson C.G.,et al.J. Cell Biol. 187:905-920(2009).
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