(DANRE) adra2db Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8JG69 |
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Gene ID | 266755 |
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Other Names | Alpha-2Db adrenergic receptor, Alpha-2Db adrenoceptor, Alpha(2Db)AR, Alpha-2Db adrenoreceptor, adra2db |
Target/Specificity | The synthetic peptide sequence is selected from aa 323-336 of HUMAN adra2db |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | adra2db |
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Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine = epinephrine > oxymetazoline. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine = epinephrine > oxymetazoline.
References
Ruuskanen J.O.,et al.Mol. Biol. Evol. 21:14-28(2004).
Ruuskanen J.O.,et al.Br. J. Pharmacol. 144:165-177(2005).
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