NPY2R Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P49146 |
---|
Gene ID | 4887 |
---|---|
Other Names | Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R |
Target/Specificity | The synthetic peptide sequence is selected from aa 29-45 of HUMAN NPY2R |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NPY2R |
---|---|
Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
References
Gerald C.,et al.J. Biol. Chem. 270:26758-26761(1995).
Gehlert D.R.,et al.Mol. Pharmacol. 49:224-228(1996).
Rose P.M.,et al.J. Biol. Chem. 270:22661-22664(1995).
Yan H.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996).
Ammar D.A.,et al.Genomics 38:392-398(1996).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.