|Other Names||Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns|
|Target/Specificity||The synthetic peptide sequence is selected from aa 420-434 of HUMAN Gnl3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.|
|Cellular Location||Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus|
|Tissue Location||Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Tsai R.Y.L.,et al.Genes Dev. 16:2991-3003(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).
Meng L.,et al.Oncogene 30:1716-1726(2011).
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