|Other Names||Type I inositol 1, 5-trisphosphate 5-phosphatase, 5PTase, INPP5A|
|Target/Specificity||The synthetic peptide sequence is selected from aa 306-320 of HUMAN INPP5A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.|
|Cellular Location||Membrane; Lipid-anchor.|
|Tissue Location||Brain; high level in Purkinje cells.|
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Provided below are standard protocols that you may find useful for product applications.
Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.
de Smedt F.,et al.FEBS Lett. 347:69-72(1994).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Laxminarayan K.M.,et al.J. Biol. Chem. 269:17305-17310(1994).
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