|Other Names||Plexin-B1, Semaphorin receptor SEP, PLXNB1, KIAA0407, PLXN5, SEP|
|Target/Specificity||The synthetic peptide sequence is selected from aa 1715-1729 of HUMAN PLXNB1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0407, PLXN5, SEP|
|Function||Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted.|
|Tissue Location||Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Ishikawa K.,et al.DNA Res. 4:307-313(1997).
Tamagnone L.,et al.Cell 99:71-80(1999).
Tamagnone L.,et al.Cell 104:321-321(2001).
Maestrini E.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:674-678(1996).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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