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MC3R Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession P41968
Additional Information
Gene ID 4159
Other Names Melanocortin receptor 3, MC3-R, MC3R
Target/Specificity The synthetic peptide sequence is selected from aa 301-315 of HUMAN MC3R
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MC3R
Function Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Brain, placental, and gut tissues.
Research Areas
Citations (0)

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Background

Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.

References

Gantz I.,et al.J. Biol. Chem. 268:8246-8250(1993).
Kopatz S.A.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Tarnow P.,et al.Obes. Facts 5:45-51(2012).
Lee Y.-S.,et al.J. Clin. Endocrinol. Metab. 87:1423-1426(2002).

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$ 80.00
$ 99.00
Cat# BP21431b
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