|Other Names||Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial, 3-oxoacid CoA-transferase 1, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase, SCOT-s, OXCT1, OXCT, SCOT|
|Target/Specificity||The synthetic peptide sequence is selected from aa 272-286 of HUMAN OXCT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.|
|Cellular Location||Mitochondrion matrix.|
|Tissue Location||Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts|
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Provided below are standard protocols that you may find useful for product applications.
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Reymond M.A.,et al.Submitted (FEB-1997) to UniProtKB.
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