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CRYZ Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q08257
Additional Information
Gene ID 1429
Other Names Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin, CRYZ
Target/Specificity The synthetic peptide sequence is selected from aa 248-262 of HUMAN CRYZ
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRYZ
Function Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
Cellular Location Cytoplasm.
Tissue Location Only very low amounts in the lens.
Research Areas
Citations (0)

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Background

Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.

References

Gonzalez P.,et al.Biochem. Biophys. Res. Commun. 191:902-907(1993).
Gonzalez P.,et al.Genomics 21:317-324(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 80.00
Cat# BP21584b
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