|Other Names||Chymase, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM|
|Target/Specificity||The synthetic peptide sequence is selected from aa 84-98 of HUMAN CMA1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.|
|Cellular Location||Secreted. Cytoplasmic granule. Note=Mast cell granules|
|Tissue Location||Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions|
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Provided below are standard protocols that you may find useful for product applications.
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
Caughey G.H.,et al.J. Biol. Chem. 266:12956-12963(1991).
Urata H.,et al.J. Biol. Chem. 266:17173-17179(1991).
Schechter N.M.,et al.J. Immunol. 152:4062-4069(1994).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Heilig R.,et al.Nature 421:601-607(2003).
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