FGF5 Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P12034 |
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Gene ID | 2250 |
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Other Names | Fibroblast growth factor 5, FGF-5, Heparin-binding growth factor 5, HBGF-5, Smag-82, FGF5 |
Target/Specificity | The synthetic peptide sequence is selected from aa 160-172 of HUMAN FGF5 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FGF5 |
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Function | Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity). |
Cellular Location | Secreted. |
Tissue Location | Expressed in neonatal brain. |
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Background
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (By similarity).
References
Haub O.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8022-8026(1990).
Zhan X.,et al.Mol. Cell. Biol. 8:3487-3495(1988).
Ozawa K.,et al.Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
de Vries C.J.M.,et al.J. Biol. Chem. 275:23939-23947(2000).
Hanada K.-I.,et al.Cancer Res. 61:5511-5516(2001).
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