EI24 Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14681 |
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Other Accession | Q08DE5, Q61070, Q4KM77 |
Gene ID | 9538 |
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Other Names | Etoposide-induced protein 24 homolog, p53-induced gene 8 protein, EI24, PIG8 |
Target/Specificity | The synthetic peptide sequence is selected from aa 27-41 of HUMAN EI24 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | EI24 |
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Synonyms | PIG8 |
Function | Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity). |
Cellular Location | Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein |
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Background
Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
References
Polyak K.,et al.Nature 389:300-306(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gentile M.,et al.Oncogene 20:7753-7760(2001).
Olsen J.V.,et al.Cell 127:635-648(2006).
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