DNASE1L2 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q92874 |
---|
Gene ID | 1775 |
---|---|
Other Names | Deoxyribonuclease-1-like 2, 3.1.21.-, DNase I homolog protein DHP1, Deoxyribonuclease I-like 2, DNase I-like 2, DNASE1L2, DHP1, DNAS1L2 |
Target/Specificity | The synthetic peptide sequence is selected from aa 219-229 of HUMAN DNASE1L2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DNASE1L2 |
---|---|
Synonyms | DHP1, DNAS1L2 |
Function | Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells. |
Cellular Location | Cytoplasm. Secreted |
Tissue Location | Preferentially expressed in the skin and up- regulated during keratinocytes differentiation. Highly abundant (at protein level) in the stratum granulosum |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.
References
Rodriguez A.M.,et al.Genomics 42:507-513(1997).
Shiokawa D.,et al.Genomics 84:95-105(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.