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NAT8L Blocking Peptide (N-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q8N9F0
Other Accession Q3UGX3, D3ZVU9
Additional Information
Gene ID 339983
Other Names N-acetylaspartate synthetase, NAA synthetase, 2.3.1.17, Camello-like protein 3, N-acetyltransferase 8-like protein, NAT8L, CML3
Target/Specificity The synthetic peptide sequence is selected from aa 79-93 of HUMAN NAT8L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAT8L
Synonyms CML3
Function Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
Cellular Location Cytoplasm. Membrane; Single- pass membrane protein. Microsome membrane; Single-pass membrane protein Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane; Single-pass membrane protein. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment
Tissue Location Expressed in brain.
Research Areas
Citations (0)

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Background

Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.

References

Hillier L.W.,et al.Nature 434:724-731(2005).
Brandenberger R.,et al.Nat. Biotechnol. 22:707-716(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Popsueva A.E.,et al.Dev. Biol. 234:483-496(2001).
Arun P.,et al.Neurochem. Int. 55:219-225(2009).

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$ 80.00
Cat# BP21925a
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