TMEM115 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q12893 |
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Other Accession | A4FUB8, Q9WUH1 |
Gene ID | 11070 |
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Other Names | Transmembrane protein 115, Placental protein 6, Protein PL6, TMEM115 (HGNC:30055) |
Target/Specificity | The synthetic peptide sequence is selected from aa 269-283 of HUMAN TMEM115 (HGNC:30055) |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TMEM115 (HGNC:30055) |
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Function | May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi. |
Cellular Location | Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein |
Tissue Location | Expressed strongly in kidney and skeletal muscle, followed by liver, placenta, pancreas, and lung, with low amounts in heart and only traces in brain (PubMed:11085536). Widely expressed with ubiquitous expression in epithelial tissues (at protein level) (PubMed:17973242). |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.
References
Lerman M.I.,et al.Cancer Res. 60:6116-6133(2000).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ivanova A.V.,et al.J. Pathol. 214:46-57(2008).
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