|Other Names||Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5, IGFBP5, IBP5|
|Target/Specificity||The synthetic peptide sequence is selected from aa 107-121 of HUMAN IGFBP5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.|
|Tissue Location||Osteosarcoma, and at lower levels in liver, kidney and brain|
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Provided below are standard protocols that you may find useful for product applications.
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Kiefer M.C.,et al.Biochem. Biophys. Res. Commun. 176:219-225(1991).
Shimasaki S.,et al.J. Biol. Chem. 266:10646-10653(1991).
Allander S.V.,et al.J. Biol. Chem. 269:10891-10898(1994).
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
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