NT5C3 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H0P0 |
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Other Accession | Q9D020 |
Gene ID | 51251 |
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Other Names | Cytosolic 5'-nucleotidase 3A, 3.1.3.5, Cytosolic 5'-nucleotidase 3, Cytosolic 5'-nucleotidase III, cN-III, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I, Uridine 5'-monophosphate hydrolase 1, p36, NT5C3A, NT5C3, P5N1, UMPH1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 302-313 of HUMAN NT5C3A |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NT5C3A |
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Synonyms | NT5C3, P5N1, UMPH1 |
Function | Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP) (PubMed:24603684). CMP seems to be the preferred substrate (PubMed:15968458). |
Cellular Location | Cytoplasm. |
Tissue Location | Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
Can act both as nucleotidase and as phosphotransferase.
References
Amici A.,et al.Blood 96:1596-1598(2000).
Marinaki A.M.,et al.Blood 97:3327-3332(2001).
Kanno H.,et al.Br. J. Haematol. 126:265-271(2004).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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