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SLC6A8 Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P48029 |
|---|---|
| Other Accession | O18875, Q8VBW1, P28570 |
| Gene ID | 6535 |
|---|---|
| Other Names | Sodium- and chloride-dependent creatine transporter 1, CT1, Creatine transporter 1, Solute carrier family 6 member 8, SLC6A8 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 200-212 of HUMAN SLC6A8 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC6A8 |
|---|---|
| Function | Creatine:sodium symporter which mediates the uptake of creatine (PubMed:7953292, PubMed:7945388, PubMed:9882430, PubMed:17465020, PubMed:22644605, PubMed:25861866). Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein |
| Tissue Location | Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Required for the uptake of creatine in muscles and brain.
References
Nash S.R.,et al.Recept. Channels 2:165-174(1994).
Sora I.,et al.Biochem. Biophys. Res. Commun. 204:419-427(1994).
Sandoval N.,et al.Genomics 35:383-385(1996).
Barnwell L.F.,et al.Gene 159:287-288(1995).
Martinez-Munoz C.,et al.Gene 418:53-59(2008).
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