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SLC2A8 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9NY64
Other Accession P58354
Additional Information
Gene ID 29988
Other Names Solute carrier family 2, facilitated glucose transporter member 8, Glucose transporter type 8, GLUT-8, Glucose transporter type X1, SLC2A8, GLUT8, GLUTX1
Target/Specificity The synthetic peptide sequence is selected from aa 280-292 of HUMAN SLC2A8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC2A8
Synonyms GLUT8, GLUTX1
Function Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity)
Tissue Location Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues
Research Areas
Citations (0)

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Background

Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).

References

Doege H.,et al.J. Biol. Chem. 275:16275-16280(2000).
Ibberson M.R.,et al.J. Biol. Chem. 275:4607-4612(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 80.00
Cat# BP22138c
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