|Other Names||Solute carrier family 2, facilitated glucose transporter member 8, Glucose transporter type 8, GLUT-8, Glucose transporter type X1, SLC2A8, GLUT8, GLUTX1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 280-292 of HUMAN SLC2A8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity)|
|Tissue Location||Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues|
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Provided below are standard protocols that you may find useful for product applications.
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).
Doege H.,et al.J. Biol. Chem. 275:16275-16280(2000).
Ibberson M.R.,et al.J. Biol. Chem. 275:4607-4612(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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