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GGA3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NZ52
Other Accession GGA3_HUMAN
Clone Names 3103102
Additional Information
Gene ID 23163
Other Names ADP-ribosylation factor-binding protein GGA3, Golgi-localized, gamma ear-containing, ARF-binding protein 3, GGA3, KIAA0154
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2318b was selected from the C-term region of human GGA3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGA3
Synonyms KIAA0154
Function Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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GGA3 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.


Wakasugi, M., et al., Biochem. Biophys. Res. Commun. 306(3):687-692 (2003).Misra, S., et al., Nature 415(6874):933-937 (2002).Puertollano, R., et al., Science 292(5522):1712-1716 (2001).Takatsu, H., et al., Biochem. Biophys. Res. Commun. 271(3):719-725 (2000).Dell'Angelica, E.C., et al., J. Cell Biol. 149(1):81-94 (2000).

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$ 80.00
Cat# BP2318b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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