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TPST1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O60507
Clone Names 3111904
Additional Information
Gene ID 8460
Other Names Protein-tyrosine sulfotransferase 1, Tyrosylprotein sulfotransferase 1, TPST-1, TPST1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2321a was selected from the N-term region of human TPST1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TPST1
Function Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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The importance of tyrosine O-sulfation in protein-protein interactions is illustrated by the sulfation of tyrosine residues in the leukocyte adhesion molecule P-selectin glycoprotein ligand-1; sulfation is required for its binding to P-selectin on activated endothelium. This enzyme represents a new class of Golgi sulfotransferases that catalyze tyrosine O-sulfation of many protein substrates involved in diverse physiologic functions including inflammation, hemostasis, body weight and reproductive physiology.


Hillier, L.W., et al., Nature 424(6945):157-164 (2003).Scherer, S.W., et al., Science 300(5620):767-772 (2003).Seibert, C., et al., Proc. Natl. Acad. Sci. U.S.A. 99(17):11031-11036 (2002).Goettsch, S., et al., Biochem. Biophys. Res. Commun. 294(3):541-546 (2002).Popovic, M., et al., Eur. J. Hum. Genet. 10(4):250-258 (2002).

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$ 80.00
Cat# BP2321a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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