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Ribophorin (RPN1) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P04843
Clone Names 3102206
Peptide ID 3102206
Additional Information
Gene ID 6184
Other Names Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1, RPN1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2409a was selected from the N-term region of human RPN1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPN1
Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Expressed in all tissues tested.
Research Areas
Citations (0)

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Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasic reticulum, that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein. RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1. The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.


Fu, J., et al., J. Biol. Chem. 275(6):3984-3990 (2000).Pekarsky, Y., et al., Cancer Res. 57(18):3914-3919 (1997).Crimaudo, C., et al., EMBO J. 6(1):75-82 (1987).

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$ 80.00
Cat# BP2409a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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