|Other Names||Caprin-1, Cell cycle-associated protein 1, Cytoplasmic activation- and proliferation-associated protein 1, GPI-anchored membrane protein 1, GPI-anchored protein p137, GPI-p137, p137GPI, Membrane component chromosome 11 surface marker 1, RNA granule protein 105, CAPRIN1, GPIAP1, GPIP137, M11S1, RNG105|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2463b was selected from the C-term region of human GPIP137 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPIAP1, GPIP137, M11S1, RNG105|
|Function||May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.|
|Cellular Location||Cytoplasm, cytosol. Cell projection, dendrite. Note=Associated with RNA granules.|
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Provided below are standard protocols that you may find useful for product applications.
GPIP137, attached to cell membranes via a GPI-anchor, may play a role in transporting nutrient from the gut lumen across the gutlining epithelial cell layer. Expression of this protein is ubiquitous.
Gessler, M., et al., Genomics 32(1):169-170 (1996).Ellis, J.A., et al., J. Biol. Chem. 270(35):20717-20723 (1995).
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