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Prohibitin (PHB1) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P35232
Clone Names 6072325
Peptide ID 6072325
Additional Information
Gene ID 5245
Other Names Prohibitin, PHB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2710a was selected from the N-term region of human PHB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHB
Function Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Cellular Location Mitochondrion inner membrane.
Tissue Location Widely expressed in different tissues.
Research Areas
Citations (0)

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Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.


Gregory-Bass,R.C., Int. J. Cancer 122 (9), 1923-1930 (2008)Ross,J.A., J. Biol. Chem. 283 (8), 4699-4713 (2008)White,J.J., Genomics 11 (1), 228-230 (1991)

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$ 80.00
Cat# BP2710a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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