|Other Names||Beta-2-microglobulin, Beta-2-microglobulin form pI 53, B2M|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2771d was selected from the C-term region of human B2M. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.|
|Cellular Location||Secreted. Note=Detected in serum and urine|
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Provided below are standard protocols that you may find useful for product applications.
Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.
Sakata,M., J. Mol. Biol. 382 (5), 1242-1255 (2008)Huang,W.C., Clin. Cancer Res. 14 (17), 5341-5347 (2008)Gattoni-Celli,S., Cancer Res. 52 (5), 1201-1204 (1992)
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