|Other Names||Selenide, water dikinase 1, Selenium donor protein 1, Selenophosphate synthase 1, SEPHS1, SELD, SPS, SPS1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP2787b was selected from the C-term region of human SEPHS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||SELD, SPS, SPS1|
|Function||Synthesizes selenophosphate from selenide and ATP.|
|Cellular Location||Isoform 1: Cell membrane. Nucleus membrane. Isoform 3: Cytoplasm.|
|Tissue Location||Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased.|
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Provided below are standard protocols that you may find useful for product applications.
SEPHS1 is an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.
Chung,H.J., J. Cell. Physiol. 209 (1), 131-141 (2006)Tamura,T., Proc. Natl. Acad. Sci. U.S.A. 101 (46), 16162-16167 (2004)Low,S.C., J. Biol. Chem. 270 (37), 21659-21664 (1995)
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