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AHSA1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O95433
Clone Names 81202003
Peptide ID 81202003
Additional Information
Gene ID 10598
Other Names Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2892a was selected from the N-term region of human AHSA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AHSA1
Synonyms C14orf3
Function Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360).
Cellular Location Cytoplasm, cytosol. Endoplasmic reticulum. Note=May transiently interact with the endoplasmic reticulum
Tissue Location Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Research Areas
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Background

AHSA1 is a cochaperone that stimulates HSP90 ATPase activity. This protein may affect a step in the endoplasmic reticulum to Golgi trafficking.

References

Wang,X.,etc,Cell 127 (4), 803-815 (2006)Panaretou,B., etc,Mol. Cell 10 (6), 1307-1318 (2002)

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$ 80.00
Cat# BP2892a
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